Alaska Airlines operates nonstop flights to a wide variety of destinations across its network. According to its official route map and destination listings, Alaska flies nonstop to cities throughout the U.S., Canada, Mexico, and Central America. For example, you’ll find direct flights from key West-Coast hubs like Seattle and Los Angeles to places such as Honolulu (Hawai‘i), Vancouver, Puerto Vallarta and Cancun. If you tell me your departure city, I can check whether Alaska offers a nonstop flight from there.