There are excellent late-night dining options in St. Louis. On weekends, Up Late is the place to go for comfort cuisine till four in the morning, which is ideal for sating appetites around midnight. After a night out, the vibrant ambiance and inventive sandwich menu of The Gramophone in The Grove are perfect. For a more traditional diner experience, Courtesy Diner is a dependable option at any time of day or night because it offers burgers, shakes, and breakfast all day, every day.